职称:讲师
学历:博士
E-mail:xiaoyaqian@hbut.edu.cn
研究方向:孤独症谱系障碍的发病机制与精准诊疗;孤独症诊断生物标记物的研发。
学习、工作经历:
肖亚倩,女,中共党员,硕士生导师,2022年入选“武汉英才”优秀青年人才。2022年获武汉大学微生物学博士学位,2022年入职湖北工业老员工命科学与健康工程学院。现从事孤独症的发病机制及精准诊疗,以及生物医药相关科研和教学工作。
2022年06月 武汉大学理学博士
2022年07月至今 湖北工业老员工命科学与健康工程学院
荣获奖励:
“武汉英才”优秀青年人才
研究课题:
[1]湖北省自然科学基金青年项目,“钼蛋白在Shank3-/-介导的孤独症中的功能与作用机制研究”,2023.06-2025.06,主持。
[2]“武汉英才”优秀青年人才项目,2023-2026,主持。
[3]湖北省重点实验室开放基金项目,“假单胞菌gtrABII操纵子调控细菌毒力及其介导细菌与宿主互作的机理研究”,2023-2025,主持。
[4]3044澳门永利集团欢迎您人才引进科研项目,“孤独症诊断生物标志物研发以及孤独症致病机制研究”,2022-2025,主持。
[5]湖北省国际科技合作计划项目,“面向儿童重大脑疾病的环境致病机制及早期筛查技术研究”,2023-2025,关键参与人员。
研究成果:
[1]Xiao Yaqian, Wang Panning, Zhu Xuesi, Xie Zhixiong*.Pseudomonas donghuensisHYSgtrA/B/IIgene cluster contributes to its pathogenicity towardCaenorhabditis elegans.International Journal of Molecular Sciences, 2021, 22(19): 10741.
[2]Xiao Yaqian†, Xiang Wang†, Ma Xuerui, Gao Donghao, Hasan Bayram, George H. Lorimer, Reza A. Ghiladi, Zhixiong Xie*, and Jun Wang*, HemN2 regulates the virulence ofPseudomonas donghuensisHYS through 7-hydroxytropolone synthesis and oxidative stress.Biology, 2024, 13(6), 373.
[3]Qin Xiangfeng, Xiao Yaqian, Ye Cheng, Jia Jingyi, Liu Xiangjiang, Liang Hongwei, Zou Guiwei, Hu Guangfu*. Pituitary action of E2 in prepubertal grass carp: Receptor specificity and signal transduction for luteinizing hormone and follicle-stimulating hormone regulation.Frontiers in Endocrinology, 2018, 9: 308.
[4]Wang Panning, Xiao Yaqian, Gao Donghao, Long Yan* and Xie Zhixiong*. The GenepaaZof the phenylacetic acid (PAA) catabolic pathway branching point andechoutside the PAA catabolon gene cluster are synergistically involved in the biosynthesis of the iron scavenger 7-hydroxytropolone inPseudomonas donghuensisHYS.International Journal of Molecular Sciences, 2023, 24(16): 12632.
[5]Zhang Xinming, Zhang Ke, Yang Ning, Xiao Yaqian, Peng Yonghong, Han Zhigang, Su Wei, Sun Guihong, Wang Jun*. Effect of natural gums on pasting, rheological, structural and hydrolysis properties of kudzu starch.Current Research in Food Science, 2023, 7: 100607.
[6]Dong Xingchen, Wu Siyi, Rao Zihuan, Xiao Yaqian, Long Yan* and Xie Zhixiong*. Insight into the high-efficiency benzo(a)pyrene degradation ability ofPseudomonas benzopyrenicaBaP3 and its application in the complete bioremediation of benzo(a)pyrene.International Journal of Molecular Sciences, 2023, 20: 15323.
[7]Teng Shiyu, Wu Tingting, Gao Donghao, Wu Siyi, Xiao Yaqian, Long Yan* and Xie Zhixiong*. Insight into the global negative regulation of Iron scavenger 7-HT biosynthesis by the SigW/RsiW system inPseudomonas donghuensisHYS.International Journal of Molecular Sciences, 2023, 24(2): 1184.
[8]Shi Ai, Liu Di, Wu Huiwen, Zhu Rui, Deng Ying, Yao Lulu, Xiao Yaqian, Lorimer George H, Ghiladi Reza A, Xu Xinjie, Zhang Rong, Xu Haiqing, Wang Jun. Serum binding folate receptor autoantibodies lower in autistic boys and positively-correlated with folate.Biomed Pharmacother, 2024, 172: 116191.
[9]Deng Wenwen, Zang Chuanru, Li Qiuchen, Sun Bo, Mei Xueping, Bai Lu, Shang Xinmiao, Deng Ying, Xiao Yaqian, Ghiladi Reza A, Lorimer George H, Zhang Xueji, Wang Jun*. Hydrothermally derived green carbon dots from broccoli water extracts: Decreased toxicity, enhanced free-radical scavenging, and anti-Inflammatory performance.ACS Biomaterials Science & Engineering, 2023, 9(3): 1307-1319.
[10]肖亚倩,李有恒,王军.白藜芦醇在创面修复中的作用研究进展.生物技术,2023.
[11]肖亚倩,马雪睿,郑艾佳,高晓杰,张倪萌,赵子文,王军.环境污染物与孤独症关联及致病机理研究进展.生命科学,2023.
[12]白璐,张月美,向往,肖亚倩,黄胜,朱红敏,王军.一氧化氮在孤独症中的作用与调控机制的研究进展.生物技术,2023.
[13]彭康,邓远翔,张嵘,肖亚倩,王军.丙戊酸在神经发育中的作用.生命的化学,2023.
[14]国家发明专利:一种草鱼下丘脑细胞体外培养方法。(公布号:CN107686830B).
[15]国家发明专利:一种黄鳝精子超低温冷冻保存液及其冷冻复苏方法。(公布号:CN107683850A).
[16]国家发明专利:一种草鱼垂体细胞体外培养方法。(公布号:CN107699544A).